Latest Publications
Long-term Relapse of Type 2 Diabetes After Roux-en-Y Gastric Bypass: Prediction and Clinical Relevance
Diabetes Care 2018 Aug;
OBJECTIVE: Roux-en-Y gastric bypass (RYGB) induces type 2 diabetes remission (DR) in 60% of patients at 1 year, yet long-term rela...
Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes
J. Pathol. 2018 Jul;
Obesity and its metabolic complications are characterized by subclinical systemic and tissue inflammation. In rodent models of obesity, inflammatio...
Gut microbiota and obesity: Concepts relevant to clinical care
Eur. J. Intern. Med. 2018 Feb;48:18-24
The composition and function of gut microbiota play a role in obesity and metabolic disease, yet the mechanisms have not been fully described. As n...
The advanced-DiaRem score improves prediction of diabetes remission 1 year post-Roux-en-Y gastric bypass
Diabetologia 2017 Jul;
AIMS/HYPOTHESIS: Not all people with type 2 diabetes who undergo bariatric surgery achieve diabetes remission. Thus it is critical...
Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue
Sci Rep 2017 Jun;7(1):3000
Adipose tissue contains a variety of immune cells, which vary in abundance and phenotype with obesity. The contribution of immune cell-derived fact...
The FAT Score, a Fibrosis Score of Adipose Tissue: Predicting Weight-Loss Outcome After Gastric Bypass
J. Clin. Endocrinol. Metab. 2017 Jul;102(7):2443-2453
Context: Bariatric surgery (BS) induces major and sustainable weight loss in many patients. Factors predicting poor weight-loss re...
Prospective assessment and histological analysis of adherent perinephric fat in partial nephrectomies
Urol. Oncol. 2017 Feb;35(2):39.e9-39.e17
OBJECTIVES: The complexity of partial nephrectomy (PN) is partly anticipated by morphometric tumor-based scores that do not consid...
Knee and hip intra-articular adipose tissues (IAATs) compared with autologous subcutaneous adipose tissue: a specific phenotype for a central player in osteoarthritis
Ann. Rheum. Dis. 2017 Jun;76(6):1142-1148
OBJECTIVES: Compared with subcutaneous adipose tissue (SCAT), infrapatellar fat pad (IFP), the main knee intra-articular adipose t...