Diabetes Care 2018 Aug;
OBJECTIVE: Roux-en-Y gastric bypass (RYGB) induces type 2 diabetes remission (DR) in 60% of patients at 1 year, yet long-term rela...
J. Pathol. 2018 Jul;
Obesity and its metabolic complications are characterized by subclinical systemic and tissue inflammation. In rodent models of obesity, inflammatio...
Eur. J. Intern. Med. 2018 Feb;48:18-24
The composition and function of gut microbiota play a role in obesity and metabolic disease, yet the mechanisms have not been fully described. As n...
Diabetologia 2017 Jul;
AIMS/HYPOTHESIS: Not all people with type 2 diabetes who undergo bariatric surgery achieve diabetes remission. Thus it is critical...
Sci Rep 2017 Jun;7(1):3000
Adipose tissue contains a variety of immune cells, which vary in abundance and phenotype with obesity. The contribution of immune cell-derived fact...
J. Clin. Endocrinol. Metab. 2017 Jul;102(7):2443-2453
Context: Bariatric surgery (BS) induces major and sustainable weight loss in many patients. Factors predicting poor weight-loss re...
Urol. Oncol. 2017 Feb;35(2):39.e9-39.e17
OBJECTIVES: The complexity of partial nephrectomy (PN) is partly anticipated by morphometric tumor-based scores that do not consid...
Ann. Rheum. Dis. 2017 Jun;76(6):1142-1148
OBJECTIVES: Compared with subcutaneous adipose tissue (SCAT), infrapatellar fat pad (IFP), the main knee intra-articular adipose t...
Int J Obes (Lond) 2017 Jun;41(6):917-925
BACKGROUND/OBJECTIVES: Circulating phospholipids and sphingolipids are implicated in obesity-related comorbidities such as insulin...
Cell Metab. 2017 Mar;25(3):673-685
Obesity-induced white adipose tissue (WAT) fibrosis is believed to accelerate WAT dysfunction. However, the cellular origin of WAT fibrosis remains...
Proc. Natl. Acad. Sci. U.S.A. 2017 Jan;114(5):E771-E780
The abundance of epicardial adipose tissue (EAT) is associated with atrial fibrillation (AF), the most frequent cardiac arrhythmia. However, both t...
J Acad Nutr Diet 2017 Jun;117(6):878-888
BACKGROUND: The European study MetaCardis aims to investigate the role of the gut microbiota in health and cardiometabolic disease...
J. Clin. Invest. 2017 Jan;127(1):293-305
Prader-Willi syndrome (PWS) is caused by a loss of paternally expressed genes in an imprinted region of chromosome 15q. Among the canonical PWS phe...
Gut 2017 Sep;66(9):1688-1696
OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is a frequent complication of morbid obesity, but its severity varies greatly...
Environ. Health Perspect. 2017 03;125(3):428-436
BACKGROUND: Exposure to persistent organic pollutants (POPs) has been associated with the progression of chronic liver diseases, y...
Int J Obes (Lond) 2016 Dec;40(12):1823-1831
BACKGROUND: Adipose tissue fibrosis is a relatively new notion and its relationship with visceral obesity and cardiometabolic alte...
J. Clin. Endocrinol. Metab. 2016 Dec;101(12):4895-4903
CONTEXT: Adults with Prader-Willi syndrome (PWS) have an increased proportion of sc fat mass compared with body mass index (BMI)-m...
Ultrasound Med Biol 2016 Oct;42(10):2401-13
We describe a novel device called the AdipoScan that was adapted from the FibroScan to specifically assess shear wave speed (SWS) in human abdomina...
N. Engl. J. Med. 2016 Jul;375(3):240-6
Patients with rare defects in the gene encoding proopiomelanocortin (POMC) have extreme early-onset obesity, hyperphagia, hypopigmentation, and hyp...
Placenta 2016 Aug;44:83-90
During pregnancy, the placenta ensures multiple functions, which are directly involved in the initiation, fetal growth and outcome of gestation. Th...