Mol. Genet. Metab. 2013 Feb;108(2):125-31
Neutral lipid storage disease with myopathy (NLSDM) is caused by a mutation in the gene encoding adipose triglyceride lipase (ATGL), and is charact...
Hypertension 2013 Feb;61(2):361-7
Inappropriate mineralocorticoid receptor (MR) activation is involved in cardiac diseases. Whether and how aldosterone is involved in the deleteriou...
J. Clin. Invest. 2013 Jan;123(1):362-79
Low-grade chronic inflammation is a major characteristic of obesity and results from deregulated white adipose tissue function. Consequently, there...
Toxicol. Lett. 2013 Jan;216(1):40-6
Lipophilic pollutants such as polychlorinated biphenyls (PCBs) accumulate in high amounts in the adipose tissue. Recent epidemiological studies cor...
Mol. Endocrinol. 2012 Dec;26(12):1980-90
The liver plays a pivotal role in the physiological adaptation to fasting and a better understanding of the metabolic adaptive responses may give h...
PLoS ONE 2012;7(11):e48221
Bariatric surgery is the most effective long term weight-loss therapy for severe and morbidly obese patients. Melanocortin-4 Receptor (MC4R) mutati...
Hepatology 2012 Nov;56(5):1751-9
UNLABELLED: Nonalcoholic fatty liver disease (NAFLD) is highly prevalent and being overweight is a significant risk factor. The ai...
J. Am. Coll. Cardiol. 2012 Oct;60(15):1381-9
OBJECTIVES: This study investigated the effect of bariatric surgery (BS)-induced weight loss on cardiac ectopic fat using 3T magne...
PLoS Genet. 2012 Sep;8(9):e1002959
Weight control diets favorably affect parameters of the metabolic syndrome and delay the onset of diabetic complications. The adaptations occurring...
Arterioscler. Thromb. Vasc. Biol. 2012 Oct;32(10):2341-9
OBJECTIVE: We aim to identify the impact of endogenous cholesteryl ester transfer protein (CETP) activity on plasma capacity to me...
Pediatr Obes 2012 Oct;7(5):374-81
OBJECTIVE: Epidemiological studies report a positive relationship between serum cystatin C and cardiovascular outcomes in adults. ...
J. Clin. Endocrinol. Metab. 2012 Sep;97(9):E1677-85
AIMS AND HYPOTHESIS: Mast cells are immune cells known for their role in several inflammatory and fibrotic diseases. Recent works ...
PLoS ONE 2012;7(7):e40394
BACKGROUND/AIMS: Cathepsin S, a protein coded by the CTSS gene, is implicated in adipose tissue biology--this protein enhances adi...
PLoS ONE 2012;7(6):e39930
BACKGROUND: Blockade of the renin-angiotensin system (RAS) reduces the incidence of type 2 diabetes mellitus. In rodents, it has b...
Obesity (Silver Spring) 2012 Jun;20(6):1200-5
Epicardial fat (EF) is an active ectopic fat depot, which has been associated with coronary atherosclerosis, and which could early influence endoth...
J. Hepatol. 2012 May;56(5):1152-8
BACKGROUND & AIMS: In addition to total body fat, the regional distribution and inflammatory status of enlarged adipose tissue are...
J. Clin. Endocrinol. Metab. 2012 Apr;97(4):1320-7
CONTEXT: Extracellular matrix (ECM) remodeling is essential for adipose tissue growth and expansion in high fat-fed mice, and ther...
J. Proteome Res. 2012 Apr;11(4):2521-32
Our understanding of the mechanisms by which nonalcoholic fatty liver disease (NAFLD) progresses from simple steatosis to steatohepatitis (NASH) is...
Environ. Health Perspect. 2012 Apr;120(4):508-14
BACKGROUND: Epidemiological studies emphasize the possible role of persistent organic pollutants (POPs) in obesity and the metabol...
PLoS ONE 2012;7(3):e30325
BACKGROUND: Liver biopsy is considered as the gold standard for assessing non-alcoholic fatty liver disease (NAFLD) histologic les...