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4 03, 2020

Hepatic stellate cell hypertrophy is associated with metabolic liver fibrosis

By |2020-11-18T16:42:00+01:00March 4, 2020|

Sci Rep. 2020 Mar 2;10(1):3850. doi: 10.1038/s41598-020-60615-0.
Hepatic fibrosis is a major consequence of chronic liver disease such as non-alcoholic steatohepatitis which is undergoing a dramatic evolution given the obesity progression worldwide, and has no treatment to date...

30 01, 2020

Autophagy inhibition blunts PDGFRA adipose progenitors’ cell-autonomous fibrogenic response to high-fat diet

By |2020-11-18T16:56:00+01:00January 30, 2020|

Autophagy. 2020 Jan 28:1-11. doi: 10.1080/15548627.2020.1717129.
Adipose tissue (AT) fibrosis in obesity compromises adipocyte functions and responses to intervention-induced weight loss...

25 01, 2020

Gut Microbiota Profile of Obese Diabetic Women Submitted to Roux-en-Y Gastric Bypass and Its Association with Food Intake and Postoperative Diabetes Remission

By |2020-11-18T16:28:40+01:00January 25, 2020|

Nutrients. 2020 Jan 21;12(2):278. doi: 10.3390/nu12020278.
Gut microbiota composition is influenced by environmental factors and has been shown to impact body metabolism. Objective: To assess the gut microbiota profile before and after Roux-en-Y gastric bypass (RYGB) and the correlation with food intake and postoperative type 2 diabetes remission (T2Dr)...

17 01, 2020

OBEDIS Core Variables Project: European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions

By |2020-11-18T16:39:02+01:00January 17, 2020|

Obes Facts. 2020;13(1):1-28. doi: 10.1159/000505342. Epub 2020 Jan 16.
Heterogeneity of interindividual and intraindividual responses to interventions is often observed in randomized, controlled trials for obesity. To address the global epidemic...

16 10, 2019

Gut microbiota of obese subjects with Prader-Willi syndrome is linked to metabolic health

By |2020-11-18T17:25:18+01:00October 16, 2019|

Gut. 2020 Jul;69(7):1229-1238. doi: 10.1136/gutjnl-2019-319322.
The gut microbiota has been implicated in the aetiology of obesity and associated comorbidities. Patients with Prader-Willi syndrome (PWS) are obese but partly protected against insulin resistance...

11 04, 2019

Phosphatidylglycerols are induced by gut dysbiosis and inflammation, and favorably modulate adipose tissue remodeling in obesity

By |2019-05-21T17:29:42+02:00April 11, 2019|

FASEB J. 2019 Apr;33(4):4741-4754
Lipidomic techniques can improve our understanding of complex lipid interactions that regulate metabolic diseases. Here, a serum phospholipidomics ...

1 04, 2019

Synergistic convergence of microbiota-specific systemic IgG and secretory IgA

By |2019-05-21T17:29:01+02:00April 1, 2019|

J. Allergy Clin. Immunol. 2019 Apr;143(4):1575-1585.e4
BACKGROUND: Commensals induce local IgA responses essential to the induction of tolerance to gut microbiota, but it remains unclea...

30 03, 2019

Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials

By |2019-05-21T17:32:38+02:00March 30, 2019|

BMJ Open 2019 Mar;9(3):e017995
OBJECTIVE: To systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes...

5 02, 2019

A Data Integration Multi-Omics Approach to Study Calorie Restriction-Induced Changes in Insulin Sensitivity

By |2019-05-21T17:31:41+02:00February 5, 2019|

Front Physiol 2018;9:1958
The mechanisms responsible for calorie restriction (CR)-induced improvement in insulin sensitivity (IS) have not been fully elucidated. Greater in...

1 09, 2018

[Monitoring adherence after weight loss surgery: Identifying factors leading to non-adherence in a cohort of 207 severely obese patients who have undergone surgery. An evaluation of severely obese patients’ adherence following weight loss surgery.]

By |2019-05-21T17:27:23+02:00September 1, 2018|

Rech Soins Infirm 2018 Sep;(134):70-77
Obese patients are increasingly being offered weight loss surgery, the success of which depends in part on the quality of a long-term follow-up aft...

18 08, 2018

Long-term Relapse of Type 2 Diabetes After Roux-en-Y Gastric Bypass: Prediction and Clinical Relevance

By |2018-09-18T15:36:25+02:00August 18, 2018|

Diabetes Care 2018 Aug;
OBJECTIVE: Roux-en-Y gastric bypass (RYGB) induces type 2 diabetes remission (DR) in 60% of patients at 1 year, yet long-term rela...

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