Nature. 2020 May;581(7808):310-315. doi: 10.1038/s41586-020-2269-x.
Microbiome community typing analyses have recently identified the Bacteroides2 (Bact2) enterotype, an intestinal microbiota configuration that is associated with systemic inflammation and has a high prevalence in loose stools in humans.
Mol Metab. 2020 Sep;39:101007. doi: 10.1016/j.molmet.2020.101007. Epub 2020 Apr 28.
Obesity is characterized by systemic and low-grade tissue inflammation. In the intestine, alteration of the intestinal barrier and accumulation of inflammatory cells in the epithelium are important contributors of gut inflammation...
PPAR Res. 2020 Apr 1;2020:9210748. doi: 10.1155/2020/9210748. eCollection 2020.
Trophoblasts, as the cells that make up the main part of the placenta, undergo cell differentiation processes such as invasion, migration, and fusion.
J Hepatol. 2020 Sep;73(3):505-515. doi: 10.1016/j.jhep.2020.04.003.
Genetic factors associated with non-alcoholic fatty liver disease (NAFLD) remain incompletely understood. To date, most genome-wide association studies...
Nat Rev Gastroenterol Hepatol. 2020 May;17(5):279-297. doi: 10.1038/s41575-020-0269-9.
Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease (NAFLD).
GigaScience. 2020 Mar 1;9(3):giaa010. doi: 10.1093/gigascience/giaa010.
Microbiome biomarker discovery for patient diagnosis, prognosis, and risk evaluation is attracting broad interest...
Sci Rep. 2020 Mar 2;10(1):3850. doi: 10.1038/s41598-020-60615-0.
Hepatic fibrosis is a major consequence of chronic liver disease such as non-alcoholic steatohepatitis which is undergoing a dramatic evolution given the obesity progression worldwide, and has no treatment to date...
Gastroenterology. 2020 May;158(7):1881-1898. doi: 10.1053/j.gastro.2020.01.049.
Gut microbiota plays a role in the pathophysiology of metabolic diseases, which include nonalcoholic fatty liver diseases, through the gut-liver axis...
Autophagy. 2020 Jan 28:1-11. doi: 10.1080/15548627.2020.1717129.
Adipose tissue (AT) fibrosis in obesity compromises adipocyte functions and responses to intervention-induced weight loss...
Nutrients. 2020 Jan 21;12(2):278. doi: 10.3390/nu12020278.
Gut microbiota composition is influenced by environmental factors and has been shown to impact body metabolism. Objective: To assess the gut microbiota profile before and after Roux-en-Y gastric bypass (RYGB) and the correlation with food intake and postoperative type 2 diabetes remission (T2Dr)...
Obes Facts. 2020;13(1):1-28. doi: 10.1159/000505342. Epub 2020 Jan 16.
Heterogeneity of interindividual and intraindividual responses to interventions is often observed in randomized, controlled trials for obesity. To address the global epidemic...
Gut. 2020 Jul;69(7):1229-1238. doi: 10.1136/gutjnl-2019-319322.
The gut microbiota has been implicated in the aetiology of obesity and associated comorbidities. Patients with Prader-Willi syndrome (PWS) are obese but partly protected against insulin resistance...
J Clin Invest. 2019 Oct 1;129(10):4032-4040
Obesity originates from an imbalance between caloric intake and energy expenditure that promotes adipose tissue expansion, which is necessary to buffer nutrient excess...
Curr Diab Rep. 2019 Jun 27;19(8):51.
Purpose of Review: The aim of this review is to summarize the current data available on the metabolic effects of fecal microbiota transplantation (FMT) including obesity and glucose metabolism in humans...
Curr Obes Rep. 2019 Sep;8(3):229-242
BACKGROUND: In this review, we summarize what is currently described in terms of gut microbiota (GM) dysbiosis modification post-bariatric surgery (BS) and their link with BS-induced clinical improvement...
Pediatr Obes 2019 05;14(5):e12496
BACKGROUND: Many genetic polymorphisms identified by genome-wide association studies for adult body mass index (BMI) have been sug...
Semin Immunopathol 2019 Apr;
Obesity is a chronic low-grade inflammatory disease (both at the systemic and adipose tissue level) that continues to rise worldwide. It is associa...
FASEB J. 2019 Apr;33(4):4741-4754
Lipidomic techniques can improve our understanding of complex lipid interactions that regulate metabolic diseases. Here, a serum phospholipidomics ...
J. Allergy Clin. Immunol. 2019 Apr;143(4):1575-1585.e4
BACKGROUND: Commensals induce local IgA responses essential to the induction of tolerance to gut microbiota, but it remains unclea...
BMJ Open 2019 Mar;9(3):e017995
OBJECTIVE: To systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes...